Sickle Cell Anemia Symptoms In Nagpur
Treatments / Multiple Myeloma Cancer In Nagpur
What is Sickle Cell Anemia Symptoms In Nagpur
Sickle cell anemia symptoms in nagpur belongs to a category of inherited conditions known as sickle cell disease. It alters the typical shape of red blood cells responsible for oxygen transport throughout the body.Ordinarily, red blood cells are pliable and round, facilitating smooth movement through blood vessels. However, in sickle cell anemia, some of these cells take on a sickle or crescent shape, becoming rigid and adhesive. This alteration can impede or obstruct blood flow.
The current treatment approach focuses on alleviating pain and mitigating disease-related complications. Nonetheless, emerging therapies offer the potential to cure individuals of this condition.
Sickle Cell Anemia Symptoms
Symptoms of sickle cell anemia typically emerge around 6 months of age and can vary among individuals, evolving over time. These symptoms encompass:
Anemia: Sickle cells are prone to breaking apart prematurely, resulting in a shortened lifespan compared to normal red blood cells. This leads to a deficit of red blood cells, known as anemia, impairing the body’s oxygen supply and causing fatigue.
Pain Episodes: Intermittent episodes of severe pain, termed pain crises, are a hallmark of sickle cell anemia. These crises arise when sickle-shaped red blood cells obstruct blood flow in small vessels, affecting the chest, abdomen, and joints. The intensity and duration of pain vary, with some experiencing infrequent episodes while others endure them frequently, necessitating hospitalization for severe cases. Chronic pain from bone and joint damage, as well as ulcers, may also afflict some individuals.
Swelling of Extremities: Reduced blood circulation due to sickle-shaped red blood cells can lead to swelling in the hands and feet.
Increased Susceptibility to Infections: Damage to the spleen by sickle cells heightens the risk of infections. Consequently, infants and children with sickle cell anemia often receive vaccinations and antibiotics to safeguard against potentially life-threatening infections like pneumonia.
Delayed Growth and Puberty: Healthy red blood cells are vital for providing oxygen and nutrients necessary for growth. A deficiency in these cells can impede growth in children and postpone puberty in teenagers.
Vision Impairment: Sickle cells can obstruct the tiny blood vessels that supply blood to the eyes, resulting in damage to the retina and vision problems.
Multiple Myeloma Treatment
Medicines
- Hydroxyurea (Droxia, Hydrea). Daily hydroxyurea reduces the frequency of pain crises and might reduce the need for blood transfusions and hospital stays. But it can increase the risk of infections. Don’t take the drug if you’re pregnant.
- L-glutamine oral powder (Endari). It helps in reducing the frequency of pain crises.
- Crizanlizumab (Adakveo). This medicine, given by injection, can help reduce the frequency of pain crises in adults and in children older than 16 years. Side effects can include nausea, joint pain, back pain and fever.
- Voxelotor (Oxbryta). This medicine is used to treat sickle cell disease in adults and in children older than 12 years. Taken by mouth, this medicine can lower the risk of anemia and improve blood flow throughout the body. Side effects can include headache, nausea, diarrhea, fatigue, rash and fever.
- Pain-relieving medicines. Your healthcare professional might prescribe narcotics to help relieve pain during sickle cell pain crises.